Selective serotonin release inhibitors (SSRIs)
These are powerful antidepressants but they also have a beneficial effect on premature ejaculation. They are used as first-line treatment for this condition and their effectiveness is often maintained for several years.
They are often taken daily and include drugs such as fluoxetone and paroxetine.
Dapoxetine (Priligy®, pictured) is the only SSRI licensed for use "on demand" (i.e. when needed) in premature ejaculation. It is normally available on the NHS, but local prescribing rules may restrict its use: you should, therefore, check with your GP or urologist whether it is available in your area.
Common side-effects of SSRIs include fatigue, drowsiness, nausea, dry mouth, diarrhoea & excessive perspiration. These are often mild and usually settle after 2-3 weeks.
SSRIs are powerful drugs. You should only take them by getting a prescription from your GP & you should have a detailed discussion about the risks & benefits before starting treatment.
Other drugs which delay ejaculation
Drugs such as tramodol, terazosin and alfuzosin have been used, but their role is unclear and, at the moment, they are not recommended for clinical use in premature ejaculation.
If there is a suspicion that premature ejaculation is a result of, or is associated with, erectile dysfunction, it may be felt necessary to treat you with appropriate medications, either alone or in combination with therapy for premature ejaculation.
Viagra®, Cialis®, Levitra® or Spedra®, and self-administered penile injections
These may also be used to help premature ejaculation but their exact role is uncertain. They do, however, improve sexual confidence and reduce performance anxiety by producing better erections (if this is a problem).
Download a lealfet about Viagra, Cialis or Levitra
Download a leaflet about penile injections