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Please note: This page is intended for healthcare professionals only. It is designed as a general educational guide and does not replace local guidance, senior clinical advice, or individual clinical judgement. Patients should not use this page as medical advice and should seek advice from an appropriate healthcare professional.

Prostate Operations

This is a very brief introduction into most common urological operations. The list below is not exhaustive of all urological operations, but the procedures an SHO will more commonly encounter.

⚠️ Postoperative care is procedure and patient-specific. Always read the operation note before taking any action. Instructions regarding catheters, drains, stents, antibiotics, anticoagulation, imaging, and follow-up may differ between patients.

Patient information leaflets

  • Prostate procedures – HERE

Endoscopic Operations (BPH / LUTS)

These procedures remove only the obstructing part of the prostate, not the entire gland. The remaining prostate tissue can continue to grow (prostatic regrowth), so some patients may develop recurrent symptoms and require further treatment in the future.

 

Prostatectomy (Complete Prostate Removal)

  • Approaches:
    • Laparoscopic / Robotic (abbreviated as RALP/RARP)
    • Open
  • Indications:
    • Benign disease – simple prostatectomy
    • Prostate cancer – radical prostatectomy

Simple prostatectomy:

  • Indication – very large prostates, failed endoscopic options
  • Open approach = Millins prostatectomy
  • Removes the adenoma only, leaving the capsule in place
  • Done very rarely nowadays due to other alternative procedures with less morbidity (such as HOLEP)
  • Recovery:
    • Greater bleeding risk than endoscopic procedures
    • Stay 2–4 days
    • Catheter remains 5–7 days
Millins prostatectomy for benign disease
Millins prostatectomy for benign disease

Radical prostatectomy:

  • RALP / RARP is standard; open used selectively
  • Removes prostate + seminal vesicles ± pelvic lymph nodes (PLND) for localised prostate cancer
  • Patients go home with a catheter – removal timing follows strict operative note instructions

⚠️ Important Warning – if catheter falls out in early post-op period → DO NOT reinsert blindly. Contact SpR/consultant urgently → risk of disrupting vesico-urethral anastomosis

  • Specific risks – this is a major operation – ileus, bleeding, lymphocele, anastomotic leak, bowel injury, hernias, urinary incontinence, erectile dysfunction
  • Recovery – stay 1–2 days for robotic
 

Other Minimally Invasive Prostate Cancer Treatments

Brachytherapy:

  • Internal radiotherapy delivered directly to the prostate for selected patients with localised prostate cancer
  • Can be performed as permanent seed implantation (low dose, LDR) or temporary high-dose treatment (HDR).
  • Minimises radiation exposure to surrounding tissues
X-ray of brachytherapy seeds

HIFU:

  • Minimally invasive treatment using focused ultrasound to destroy prostate tissue.
  • Used in selected patients with localised prostate cancer, usually in specialist centres.
 

Prostate Biopsy

  • Performed for suspected prostate cancers (elevated PSA or MRI-visible lesions)
  • Usually done under LA, but can be done under GA
  • Risks:
    • Common – haematuria, blood in stool, haematospermia (latter can be for several weeks), retention, need for repeat procedure / further surveillance / treatment
    • Serious – sepsis, clot retention

Approaches:

Transperineal (TP) Biopsy:

  • Increasingly preferred due to lower infection risk
  • Patients are in lithotomy position
  • Needle passes through perineum
  • Useful for MRI-targeted biopsies

Transrectal (TRUS) Biopsy:

  • Ultrasound-guided biopsy via the rectum
  • Patients in lateral decubitus position
  • Higher infection risk → requires antibiotic prophylaxis